Matrix Metalloproteinases Activities in Hypertension
نویسندگان
چکیده
منابع مشابه
Expression and Activities of Matrix Metalloproteinases
Hui Bin Sun,1,2 Razi Nalim,3 and Hiroki Yokota1,2,3 1Department of Biomedical Engineering, Indiana University–Purdue University Indianapolis, Indianapolis, Indiana, USA 2Department of Anatomy and Cell Biology, Indiana University–Purdue University Indianapolis, Indianapolis, Indiana, USA 3Department of Mechanical Engineering, Indiana University–Purdue University Indianapolis, Indianapolis, India...
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Matrix metalloproteinases (MMPs) are a family of neutral proteinases that are important in normal development, cellular differentiation or migration, angiogenesis, neurogenesis, wound repair, and a wide range of pathological processes such as oxidative stress and neuroinflammation. MMPs have been demonstrated to increase the permeability of the blood–brain barrier (BBB) by degrading the c...
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Pulmonary arterial hypertension (PAH) results from persistent vasoconstriction, smooth muscle growth and extracellular matrix (ECM) remodelling of pulmonary arteries (PAs). Matrix metalloproteinases (MMPs) are matrix-degrading enzymes involved in ECM turnover, and in smooth muscle cell (SMC) and endothelial cell migration and proliferation. MMP expression and activity are increased in experimen...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2011
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.110.162032